Micrography characterization and chemical analysis of a traditional eye drops sold in town Abidjan of Côte d’Ivoire

N’dri Marcelline ADIKO-TAPE, Wacothon Karime COULIBALY, Daouda TOURE, Calixte Bahi, Aminata AKOUBET-OUAYOGODE, Néhémie Ollo POODA, Amont Landry Claude KABLAN, Diénéba KONE-BAMBA

Résumé


It is important to evaluate traditional eye medicine because of their potential iatrogenic properties linked to their composition and method of storage, which can lead to harmful effects that are sometimes irreversible on the eye. Thus, the objective of this work was to study the phytochemistry and characterization of traditional eye drops (TED) of unknown composition. The tests were carried out from a preparation 10% of TED extract. Macroscopic and microscopic characterizations were performed as well as chemical analysis by HPLC-QTOF-MS. Results showed that TED has a cloudy reddish appearance, the smell is flavored somewhat reminiscent of lemon with a slightly sour taste. Thick branched fibers, covering hairs, calcium oxalate and starch grains were observed under the microscope. Molecules such as burnamine, picralin, uncarin C; quercetin 3-O-glucuronide, apigenin 7-O-methylglucuronide, luteolin 7-glucuronide and 3,4-dimethoxycinnamic acid have been identified in TED.


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