Reactivity of chiral functionalized pyrazoles: Alcohol protection

Abstract

Having an original route to chiral pyrazoles possessing aldehyde and alcohol functions, we wished to investigate the functionalization potentialities of these new compounds. Protection reactions of the free alcohol function were performed on the compound and the acylation was successful and constitutes a good route for the functionalization of chiral pyrazoles.

Keywords: Pyrazole, protection, alkylation and acylation reactions